CHK1-IN-11
CHK1-IN-11 (Compound 1) is an orally active, checkpoint kinase 1 (CHK1) inhibitor. CHK1-IN-11 is useful for the study of cancers with oncogene amplification[1].
Product Specifications
CAS Number
[3017958-71-0]
UNSPSC
12352005
Target
Checkpoint Kinase (Chk)
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
COC1=C(C2=CC(NC3=NC=C(C#N)N=C3)=NN2)C(O[C@@H]4CC[C@@H](C4)N)=CC(C)=N1
Molecular Formula
C20H22N8O2
Molecular Weight
406.44
References & Citations
[1]Eric F. Connor, et al. Checkpoint kinase 1 (chk1) inhibitor pharmaceutical composition. WO2024211271A1. USA. 2024-04-02.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Chk1
Curated Selection
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