FANFT
FANFT is an orally active and potent uroepithelial carcinogen. FANFT is metabolized to ANFT in vivo, which induces gene mutations and malignant cell transformation. FANFT efficiently induces bladder tumors in mice[1].
Product Specifications
CAS Number
24554-26-5
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=CNC1=NC(C2=CC=C([N+]([O-])=O)O2)=CS1
Molecular Formula
C8H5N3O4S
Molecular Weight
239.21
References & Citations
[1]Mickey DD, et al. In vitro characterization of four N-[4- (5-nitro-2-furyl) -2-thiazolyl] formamide (FANFT) induced mouse bladder tumors. J Urol. 1982 Jun;127 (6) :1233-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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