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3′-Deoxy CTP (trisodium)

3′-Deoxy CTP trisodium is the sodium salt form of 3′-Deoxy CTP (HY-171587) . 3′-Deoxy CTP trisodium is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP trisodium can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP trisodium can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs[1].

Product Specifications

UNSPSC

12352005

Target

HCV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O[C@@H]1C[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O[C@H]1N2C(N=C(N)C=C2)=O

Molecular Formula

C9H13N3Na3O13P3

Molecular Weight

533.10

References & Citations

[1]Deval J, et al. Pyrophosphorolytic excision of nonobligate chain terminators by hepatitis C virus NS5B polymerase. Antimicrob Agents Chemother. 2007 Aug;51 (8) :2920-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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