CDA-IN-1

CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) . CDA-IN-1 exhibits antifungal activity. It can inhibit fungal growth by suppressing the activity of fungal CDA, activating the plant immune response, and accumulating reactive oxygen species (ROS) . At a concentration of 100 μM, CDA-IN-1 can achieve inhibition rates of 86.9% and 74.5% against PxCDA1 and PxCDA2 of P. xanthii, respectively. CDA-IN-1 can be applied to the research in the field of controlling plant fungal diseases, such as the research on diseases like cucurbit powdery mildew and tomato gray mold [1].