Mal-PNU-159682
Mal-PNU-159682 is a Drug-Linker Conjugates for ADC, composes of ADC linker (maleimide) and ADC cytotoxin PNU-159682 (HY-16700), and has anti-tumor activity[1].
Product Specifications
CAS Number
[1204819-90-8]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(NCCN5C(C=CC5=O)=O)=O)(O)C[C@@H]4O[C@H]6C[C@]7([H])N8[C@]([C@H](OCC8)OC)([H])O[C@]7([H])[C@@H](O6)C
Molecular Formula
C37H39N3O14
Molecular Weight
749.72
References & Citations
[1]Holte D, et al. Evaluation of PNU-159682 antibody drug conjugates (ADCs) . Bioorg Med Chem Lett. 2020 Dec 15;30 (24) :127640.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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