Mal-Val-Ala-amide- (3) PEA-PNU-159682
Mal-Val-Ala-amide- (3) PEA-PNU-159682 is a Drug-Linker Conjugates for ADC, composes of ADC linker (Mal-Val-Ala-amide- (3) PEA) and ADC cytotoxin PNU-159682 , and has anti-tumor activity[1].
Product Specifications
CAS Number
2682939-56-4
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(NCCC5=CC(NC([C@H](C)NC([C@H](C(C)C)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=CC=C5)=O)(O)C[C@@H]4O[C@H]7C[C@]8([H])N9[C@]([C@H](OCC9)OC)([H])O[C@]8([H])[C@@H](O7)C
Molecular Formula
C53H60N6O17
Molecular Weight
1053.07
References & Citations
[1]Holte D, et al. Evaluation of PNU-159682 antibody drug conjugates (ADCs) . Bioorg Med Chem Lett. 2020 Dec 15;30 (24) :127640.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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