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Mal-Val-Ala-amide- (3) PEA-PNU-159682

Mal-Val-Ala-amide- (3) PEA-PNU-159682 is a Drug-Linker Conjugates for ADC, composes of ADC linker (Mal-Val-Ala-amide- (3) PEA) and ADC cytotoxin PNU-159682 (HY-16700), and has anti-tumor activity[1].

Product Specifications

CAS Number

[2682939-56-4]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(NCCC5=CC(NC([C@H](C)NC([C@H](C(C)C)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=CC=C5)=O)(O)C[C@@H]4O[C@H]7C[C@]8([H])N9[C@]([C@H](OCC9)OC)([H])O[C@]8([H])[C@@H](O7)C

Molecular Formula

C53H60N6O17

Molecular Weight

1053.07

References & Citations

[1]Holte D, et al. Evaluation of PNU-159682 antibody drug conjugates (ADCs) . Bioorg Med Chem Lett. 2020 Dec 15;30 (24) :127640.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Curated Selection

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