Metahexestrol
Metahexestrol is an estrogen receptor (E2R) inhibitor with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cells (ED50 = 1.0 μM) . Additionally, Metahexestrol also exhibits inhibitory effects in estrogen receptor-negative MDA-MB-231 cells, and its antiproliferative activity cannot be reversed by estrogen, suggesting that its mechanism of action may be partially independent of the E2R pathway. Metahexestrol can be used in research on estrogen-dependent breast cancer[1].
Product Specifications
CAS Number
[71953-72-5]
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CC[C@H](C1=CC(O)=CC=C1)[C@H](C2=CC(O)=CC=C2)CC
Molecular Formula
C18H22O2
Molecular Weight
270.37
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-171477/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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