RS-57067
RS-57067 is a COX-2 inhibitor with a Ki of 16.9 μM. RS-57067 reduces the production of prostaglandins (such as PGE2) by inhibiting COX-2, thereby alleviating the inflammatory response. RS-57067 can be used in the research of inflammatory and immune diseases[1].
Product Specifications
CAS Number
179382-91-3
UNSPSC
12352005
Target
COX
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C1C=CC(CC2=CC(C)=C(N2C)C(C3=CC=C(C=C3)Cl)=O)=NN1
Molecular Formula
C18H16ClN3O2
Molecular Weight
341.79
References & Citations
[1]So OY, et al. The dynamics of prostaglandin H synthases. Studies with prostaglandin h synthase 2 Y355F unmask mechanisms of time-dependent inhibition and allosteric activation. J Biol Chem. 1998 Mar 6;273 (10) :5801-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
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