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CC-1069

CC-1069, a structural analog of thalidomide (HY-14658), is a TNF-α inhibitor that inhibits endothelial. CC-1069 can be used to study angiogenesis-dependent tumors such as gliomas[1].

Product Specifications

CAS Number

[167887-03-8]

UNSPSC

12352005

Target

TNF Receptor

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

O=C(CC(N1C(C2=C(C1=O)C=CC=C2)=O)C3=CC=C(C(OC)=C3)OC)N

Molecular Formula

C19H18N2O5

Molecular Weight

354.36

References & Citations

[1]Moreira AL, et al. Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro. J Neurooncol. 1999 Jun;43 (2) :109-14.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-171468/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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