Win 45164
Win 45164 is an orally active glucocorticoid receptor (Glucocorticoid Receptor) ligand with the activity of inhibiting the pituitary - adrenal axis. It can promote liver glycogen deposition and thymus involution in adrenalectomized male rats. Meanwhile, Win 45164 has anti - inflammatory effects. It can be used in the research of inflammatory and neurological diseases[1].
Product Specifications
CAS Number
[83880-39-1]
UNSPSC
12352005
Target
Glucocorticoid Receptor
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(C1CC=C2C(C1C(C)=O)CCC3=CC4=C(CC32C)C=NN4C5=CC=C(C=C5)F)C
Molecular Formula
C26H27FN2O2
Molecular Weight
418.50
References & Citations
[1]Schane HP, et al. Glucocorticoid/antiinflammatory activities of nonsteroidal phenylpyrazoles in the rat. Steroids. 1985 Feb;45 (2) :171-85.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-171460/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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