WR-27653
WR-27653 (RC-12) is a derivative of Catechol with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model. WR-27653 has antimalarial activity[1][2].
Product Specifications
CAS Number
6042-36-0
Product Name Alternative
RC-12
UNSPSC
12352101
Target
Drug Derivative; Parasite
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
BrC1=C(N(CCN(CC)CC)CCN(CC)CC)C=C(OC)C(OC)=C1
Molecular Formula
C20H36BrN3O2
Molecular Weight
430.42
References & Citations
[1]Werbel LM, et al. Synthesis and physical properties of the antimalarial agent 4- (2-bromo-4,5-dimethoxyphenyl) -1,1,7,7-tetraethyldiethylenetriamine (RC-12) (WR-27,653) . J Pharm Sci. 1967 Oct;56 (10) :1335-7. |[2]Dong Y, et al. Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12) . ACS Omega. 2022 Mar 30;7 (14) :12401-12411.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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