WR-27653
WR-27653 (RC-12) is a derivative of Catechol with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model. WR-27653 has antimalarial activity[1][2].
Product Specifications
CAS Number
6042-36-0
Product Name Alternative
RC-12
UNSPSC
12352101
Target
Drug Derivative; Parasite
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
BrC1=C(N(CCN(CC)CC)CCN(CC)CC)C=C(OC)C(OC)=C1
Molecular Formula
C20H36BrN3O2
Molecular Weight
430.42
References & Citations
[1]Werbel LM, et al. Synthesis and physical properties of the antimalarial agent 4- (2-bromo-4,5-dimethoxyphenyl) -1,1,7,7-tetraethyldiethylenetriamine (RC-12) (WR-27,653) . J Pharm Sci. 1967 Oct;56 (10) :1335-7. |[2]Dong Y, et al. Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12) . ACS Omega. 2022 Mar 30;7 (14) :12401-12411.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2719403 1.0 µg DNA
ZNF608 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 