RMGPa-IN-1

RMGPa-IN-1 (Compound 10C) is a rabbit muscle glycogen phosphorylase a (RMGPa) inhibitor with an IC50 value of 82.5 μM. RMGPa-IN-1 is promising for research of diabetes[1].

Product Specifications

CAS Number

[958237-73-5]

UNSPSC

12352211

Target

Phosphorylase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

CCCOC([C@]12[C@]([C@H]([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H]([C@@H](C4)O)O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O

Molecular Formula

C33H54O4

Molecular Weight

514.78

References & Citations

[1]Wen X, et al. Pentacyclic triterpenes. Part 5: synthesis and SAR study of corosolic acid derivatives as inhibitors of glycogen phosphorylases. Bioorg Med Chem Lett. 2007 Nov 1;17 (21) :5777-82.