6-Alkyne-F-araNAD

6-Alkyne-F-araNAD is an irreversible inhibitor of CD38. 6-Alkyne-F-araNAD helps other fluorescent probes (such as SR101−F-araNMN) to more clearly observe the localization of intracellular CD38[1].

Product Specifications

CAS Number

[1119281-04-7]

UNSPSC

12352005

Target

CD38

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@H]([C@@H](O)[C@H]2F)O[C@H]2[N+]3=CC=CC(C(N)=O)=C3)([O-])=O)(O)=O)O[C@H]1N(C=N4)C5=C4C(NCC#C)=NC=N5

Molecular Formula

C24H28FN7O13P2

Molecular Weight

703.46

References & Citations

[1]Shrimp JH, et al. Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. J Am Chem Soc. 2014 Apr 16;136 (15) :5656-63.