P38-α MAPK-IN-10
P38-α MAPK-IN-10 (Compound 6) is the inhibitor for p38α with an IC50 of 4 nM[1].
Product Specifications
CAS Number
[200801-77-0]
UNSPSC
12352005
Target
P38 MAPK
Related Pathways
MAPK/ERK Pathway
Field of Research
Inflammation/Immunology
Smiles
ClC1=CC=C(C2=C(C3=CC=NC(NC4CCCCC4)=N3)N(CCC)C(C5CCNCC5)=N2)C=C1Cl
Molecular Formula
C27H34Cl2N6
Molecular Weight
513.51
References & Citations
[1]Basant N, et al., Modeling the binding affinity of p38α MAP kinase inhibitors by partial least squares regression. Chem Biol Drug Des. 2012 Sep;80 (3) :455-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38α
Curated Selection
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