P38 Kinase inhibitor 7
P38 Kinase inhibitor 7 (Comp:XXXIX) is the inhibitor for p38α with an IC50 of 5.25 nM. p38 Kinase inhibitor 7 inhibits TNFα production in cell THP-1 with an IC50 of 5.88 nM[1].
Product Specifications
CAS Number
[815595-14-3]
UNSPSC
12352005
Target
P38 MAPK
Related Pathways
MAPK/ERK Pathway
Field of Research
Inflammation/Immunology
Smiles
FC1=CC=C(C2=C(C3=CC=NC(NCC(C)(CN(C)C)C)=N3)N4C=COC4=N2)C=C1
Molecular Formula
C22H25FN6O
Molecular Weight
408.47
References & Citations
[1]Ashwell M, et al., Imidazothiazoles and imidazoxazole derivatives as inhibitors of p38. WO2004110990
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
