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Casein kinase 1δ-IN-28

Casein kinase 1δ-IN-28 (Compound 4) is the inhibitor for CK1ε with an IC50 of 0.0146 μM. Casein kinase 1δ-IN-28 exhibits a metabolite rate in human liver microsomes of 52%[1].

Product Specifications

CAS Number

1095750-94-9

UNSPSC

12352005

Target

Casein Kinase

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Field of Research

Cancer; Metabolic Disease

Smiles

FC1=CC=C(C2=C(C3=CC=NC=C3)N4N=C(N5CCNC(C)(C5)C)C=CC4=N2)C=C1

Molecular Formula

C23H23FN6

Molecular Weight

402.47

References & Citations

[1]Vaz RJ, et al., Decreasing the CYP2D6 contribution to metabolism of a CK1ε inhibitor. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3681-3684.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CK1

Frequently Asked Questions

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