Casein kinase 1δ-IN-28
Casein kinase 1δ-IN-28 (Compound 4) is the inhibitor for CK1ε with an IC50 of 0.0146 μM. Casein kinase 1δ-IN-28 exhibits a metabolite rate in human liver microsomes of 52%[1].
Product Specifications
CAS Number
[1095750-94-9]
UNSPSC
12352005
Target
Casein Kinase
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Field of Research
Cancer; Metabolic Disease
Smiles
FC1=CC=C(C2=C(C3=CC=NC=C3)N4N=C(N5CCNC(C)(C5)C)C=CC4=N2)C=C1
Molecular Formula
C23H23FN6
Molecular Weight
402.47
References & Citations
[1]Vaz RJ, et al., Decreasing the CYP2D6 contribution to metabolism of a CK1ε inhibitor. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3681-3684.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1
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