KRAS G12D inhibitor 26
KRAS G12D inhibitor 26 is a modulator of Kras, targeting Kras (G12D) with an IC50 ≤ 100 nM[1].
Product Specifications
CAS Number
[2972625-49-1]
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1[C@@]2(CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6CC7=C(Cl)C(C(N(C)C)=O)=NN7CCC6)=C3C1)C8=CC=CC=C8CCC2
Molecular Formula
C35H44ClFN8O2
Molecular Weight
663.23
References & Citations
[1]Kras modulators and uses thereof. 2023-08-17. Publication of WO2023154766A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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