CDD-1281
CDD-1281 is a highly potent and selective BMPR2 kinase inhibitor with an IC50 of 1.2 nM. CDD-1281 can effectively inhibit BMP-mediated gene expression[1].
Product Specifications
CAS Number
3034215-91-0
UNSPSC
12352005
Target
TGF-β Receptor
Related Pathways
TGF-beta/Smad
Field of Research
Others
Smiles
O=C(C1=CC=CC(CNC(C2=CC3=C(N=C(N3C4CCCC4)C5=CC6=C(C=NC=C6)C=C5)C=C2)=O)=C1)N
Molecular Formula
C30H27N5O2
Molecular Weight
489.57
References & Citations
[1]Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Feb 9;66 (3) :2143-2160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-90618MFV610 0.1 mL
Rabbit Monoclonal CD229/SLAMF3/Lymphocyte Antigen 9 Antibody (017) [mFluor Violet 610 SE]
Sign In for Pricing
View Details 
K4267205 3x 1.0 µg
Trim61 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details 