MPGES1-IN-9
MPGES1-IN-9 (compound 1_8) is a mPGES1 inhibitor (IC50=0.5 μM), which can be used in anti-inflammatory research[1].
Product Specifications
CAS Number
556033-92-2
UNSPSC
12352005
Target
PGE synthase
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(CSC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)N=N1)C4=CNC5=C4C=CC=C5
Molecular Formula
C25H18N4OS
Molecular Weight
422.50
References & Citations
[1]He S, et al. Discovery of highly potent microsomal prostaglandin e2 synthase 1 inhibitors using the active conformation structural model and virtual screen. J Med Chem. 2013 Apr 25;56 (8) :3296-309.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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