CP-611,781
CP-611,781 is a diol metabolite of ezlopitant alkene (CJ-12,458) . In human liver microsomes, the apparent KM value of 5.4 μM for the formation of CP-611,781[1].
Product Specifications
CAS Number
368454-88-0
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
COC(C=CC(C(C)(O)CO)=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C31H38N2O3
Molecular Weight
486.65
References & Citations
[1]Obach RS. Cytochrome P450-catalyzed metabolism of ezlopitant alkene (CJ-12,458), a pharmacologically active metabolite of ezlopitant: enzyme kinetics and mechanism of an alkene hydration reaction. Drug Metab Dispos. 2001 Jul;29 (7) :1057-67.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![VPS35 Rabbit Monoclonal Antibody [Clone ID: 23GB4260]](https://cdn.genprice.uk/products/937/6868c301994c49e6dc3ed235/imageurl/ta425337.webp)
TA425337 100 µL
VPS35 Rabbit Monoclonal Antibody [Clone ID: 23GB4260]
Sign In for Pricing
View Details ![MMP1 Mouse Monoclonal Antibody [Clone ID: 6A5]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fbe9f/imageurl/am06648su-n.webp)
![BMAL1 (ARNTL) Mouse Monoclonal Antibody [Clone ID: 1C5]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fbdde/imageurl/am06432su-n.webp)
AM06432SU-N 100 µL
BMAL1 (ARNTL) Mouse Monoclonal Antibody [Clone ID: 1C5]
Sign In for Pricing
View Details 
LC432589 20 µg
Caveolin 1 (CAV1) (NM_001172895) Human Over-expression Lysate
Sign In for Pricing
View Details