BD-Oligo
BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo[1].
Product Specifications
CAS Number
1357578-02-9
UNSPSC
12352005
Target
Fluorescent Dye
Related Pathways
Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
98.18
Smiles
OC(C(OCC)=CC=C1)=C1/C=C/C2=[N]3C(C(C)=C2)=CC4=CC=C(CCC(OCC(Cl)(Cl)Cl)=O)[N-]4[B+3]3([F-])[F-]
Molecular Formula
C25H24BCl3F2N2O4
Molecular Weight
571.64
References & Citations
[1]Teoh CL, et al. Chemical Fluorescent Probe for Detection of Aβ Oligomers. J Am Chem Soc. 2015 Oct 28;137 (42) :13503-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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