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JC168

JC168 is a phenyl analog of peloruside and serves as a microtubule inhibitor, demonstrating antiproliferative and anticancer activities. JC168 promotes tubulin polymerization, thereby interfering with microtubule dynamics, and can be utilized in research related to microtubule-associated disorders[1].

Product Specifications

CAS Number

[1784751-83-2]

UNSPSC

12352211

Target

Microtubule/Tubulin

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O[C@@H]1C(O[C@H](/C(C)=C\[C@@H](CC)CO)C[C@@H](OC)C[C@H](O)C(C)(C)C2=CC=CC(C[C@H]1O)=C2)=O

Molecular Formula

C26H40O7

Molecular Weight

464.59

References & Citations

[1]Johan VDE, et al. Peloruside analogs, WO2015079009A1, 2015-06-04

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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