MC-Val-Cit-PAB-Sunitinib

MC-Val-Cit-PAB-Sunitinib is the conjugate of a payload Sunitinib (HY-10255A) and a linker. MC-Val-Cit-PAB-Sunitinib can be used for synthesis of HR97-Sunitinib[1].

Product Specifications

UNSPSC

12352005

Target

Target Protein Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Neurological Disease

Smiles

O=C(NCC[N+](CC)(CC1=CC=C(NC([C@@H](NC([C@H](C(C)C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)CCCNC(N)=O)=O)C=C1)CC)C3=C(NC(/C=C4C(NC5=C\4C=C(C=C5)F)=O)=C3C)C

Molecular Formula

C50H66FN10O8+

Molecular Weight

954.12

References & Citations

[1]Hsueh HT, et al., Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats. J Control Release. 2023 Oct;362:371-380.