NSC 357754
NSC 357754 is an inhibitor of Claudin. NSC 357754 can increase the transepithelial electrical resistance of cells and reduce the permeability of specific cations. NSC 357754 can be used in the research of intestinal diseases mediated by Claudin-2 and/or Claudin-15[1].
Product Specifications
CAS Number
2938216-28-3
UNSPSC
12352005
Target
Claudin
Related Pathways
Cytoskeleton
Field of Research
Metabolic Disease
Smiles
N=C(C1=CC2=C(OC(/C=C/C3=CC=C(C4=CC5=CC(C(N)=N)=CC=C5O4)C=C3)=C2)C=C1)N
Molecular Formula
C26H20N4O2
Molecular Weight
420.46
References & Citations
[1]Christopher R, et al. Claudin inhibitors and methods of use thereof. WO2023102209A1. 2023-06-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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