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NSC 357754

NSC 357754 is an inhibitor of Claudin. NSC 357754 can increase the transepithelial electrical resistance of cells and reduce the permeability of specific cations. NSC 357754 can be used in the research of intestinal diseases mediated by Claudin-2 and/or Claudin-15[1].

Product Specifications

CAS Number

2938216-28-3

UNSPSC

12352005

Target

Claudin

Related Pathways

Cytoskeleton

Field of Research

Metabolic Disease

Smiles

N=C(C1=CC2=C(OC(/C=C/C3=CC=C(C4=CC5=CC(C(N)=N)=CC=C5O4)C=C3)=C2)C=C1)N

Molecular Formula

C26H20N4O2

Molecular Weight

420.46

References & Citations

[1]Christopher R, et al. Claudin inhibitors and methods of use thereof. WO2023102209A1. 2023-06-08.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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