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PRMT3-IN-5

PRMT3-IN-5 (Compound 14) is an allosteric PRMT3 inhibitor (IC50: 291 nM) . PRMT3-IN-5 can be used for investigating PRMT3's biological functions and disease associations[1].

Product Specifications

CAS Number

[2204250-25-7]

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Smiles

O=C(NCCC1(CCCCC1)CN)NC2=CC3=C(C=NC=C3)C=C2

Molecular Formula

C19H26N4O

Molecular Weight

326.44

References & Citations

[1]Kaniskan HÜ, et al. Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3) . J Med Chem. 2018 Feb 8;61 (3) :1204-1217.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PRMT3

Curated Selection

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