PRMT3-IN-5
PRMT3-IN-5 (Compound 14) is an allosteric PRMT3 inhibitor (IC50: 291 nM) . PRMT3-IN-5 can be used for investigating PRMT3's biological functions and disease associations[1].
Product Specifications
CAS Number
[2204250-25-7]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Smiles
O=C(NCCC1(CCCCC1)CN)NC2=CC3=C(C=NC=C3)C=C2
Molecular Formula
C19H26N4O
Molecular Weight
326.44
References & Citations
[1]Kaniskan HÜ, et al. Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3) . J Med Chem. 2018 Feb 8;61 (3) :1204-1217.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-171132/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT3
Curated Selection
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