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NSD2-PWWP1-IN-1

NSD2-PWWP1-IN-1 (compound 31) is a potent NSD2-PWWP1 inhibitor with an IC50 value of 0.64 µM. NSD2-PWWP1-IN-1 has the potential for the research of cancer[1].

Product Specifications

CAS Number

2797183-30-1

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Field of Research

Cancer

Purity

98.72

Smiles

N#CC1=C2C=CC=CC2=C(C3=C(C4=C(C)C=C(CNC(C)(C)C)C=C4C)N=CN3C)C=C1

Molecular Formula

C28H30N4

Molecular Weight

422.56

References & Citations

[1]Li N, et al. Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors. J Med Chem. 2022 Jul 14;65 (13) :9459-9477.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature, keep dry and cool

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NSD2/MMSET/WHSC1

Available Sizes

Frequently Asked Questions

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