Pyrone-211
Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway[1].
Product Specifications
CAS Number
90632-45-4
UNSPSC
12352005
Target
Aldose Reductase; GPR84
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Purity
99.32
Smiles
O=C1OC(CCCCCCC)=CC(O)=C1
Molecular Formula
C12H18O3
Molecular Weight
210.27
References & Citations
[1]Dudkina N, et al. Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway. Cell Chem Biol. 2025 Jan 16;32 (1) :126-144.e18.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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