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Pyrone-211

Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway[1].

Product Specifications

CAS Number

90632-45-4

UNSPSC

12352005

Target

Aldose Reductase; GPR84

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Purity

99.32

Smiles

O=C1OC(CCCCCCC)=CC(O)=C1

Molecular Formula

C12H18O3

Molecular Weight

210.27

References & Citations

[1]Dudkina N, et al. Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway. Cell Chem Biol. 2025 Jan 16;32 (1) :126-144.e18.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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