Glucocorticoid receptor agonist-6
Glucocorticoid receptor agonist-6 (Compound A) is a Glucocorticoid receptor (GR) agonist. Glucocorticoid receptor agonist-6 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
2117643-80-6
UNSPSC
12352128
Target
ADC Payload; Glucocorticoid Receptor
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=P(O)(O)CCCCCCCCCCSC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@H](C2)O)([C@@]4(C([C@H](C3)F)=CC(C=C4)=O)C)F)([H])C[C@H]1C)C)OC(CC)=O)=O
Molecular Formula
C34H51F2O8PS
Molecular Weight
688.80
References & Citations
[1]Brandish PE, et al. Development of Anti-CD74 Antibody-Drug Conjugates to Target Glucocorticoids to Immune Cells. Bioconjug Chem. 2018 Jul 18;29 (7) :2357-2369.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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