(S) -YNT-3708
(S) -YNT-3708, the S-enantiomer of YNT-3708, with low activity for OX1R and OX2R (EC50 = 3595 nM and 1661 nm, respectively) [1].
Product Specifications
CAS Number
[2923138-00-3]
UNSPSC
12352005
Target
Orexin Receptor (OX Receptor)
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N(C)[C@H]1CCCC2=C1C=C(NS(=O)(C3=CC(/C=C/C(NC4=CC=NC=C4)=O)=CC=C3OC)=O)C=C2)CC5=CC=CC(OC)=C5
Molecular Formula
C35H36N4O6S
Molecular Weight
640.75
References & Citations
[1]Keita Iio, et al. Design and Synthesis of Orexin 1 Receptor-Selective Agonists. J Med Chem. 2023 Apr 27;66 (8) :5453-5464.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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