PAD2-IN-2 (TFA)
PAD2-IN-2 (cis-isomer of 1) TFA is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 TFA possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 TFA inhibits histone H3-citrullination[1].
Product Specifications
UNSPSC
12352005
Target
Protein Arginine Deiminase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C=C1)/N=N\C2=CC=CC=C2)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N.O=C(O)C(F)(F)F
Molecular Formula
C28H27ClF3N7O3
Molecular Weight
602.01
References & Citations
[1]Santanu Mondal, et al. Photochemical Control of Protein Arginine Deiminase (PAD) Activity. ACS Chem Biol. 2018 Apr 20;13 (4) :1057-1065.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-171002A/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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