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PAD2-IN-2 (TFA)

PAD2-IN-2 (cis-isomer of 1) TFA is a protein arginine deiminase 2 (PAD2) inhibitor. PAD2-IN-2 TFA possess an azobenzene photoswitch to optically control PAD activity. PAD2-IN-2 TFA inhibits histone H3-citrullination[1].

Product Specifications

UNSPSC

12352005

Target

Protein Arginine Deiminase

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

O=C(C1=CC=C(C=C1)/N=N\C2=CC=CC=C2)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N.O=C(O)C(F)(F)F

Molecular Formula

C28H27ClF3N7O3

Molecular Weight

602.01

References & Citations

[1]Santanu Mondal, et al. Photochemical Control of Protein Arginine Deiminase (PAD) Activity. ACS Chem Biol. 2018 Apr 20;13 (4) :1057-1065.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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