ROR1 ligand-1
ROR1 ligand-1 (9-1) is a ligand for PROTACT ROR1 degrader-1. ROR1 ligand-1 connects with VHL-type or CRBN ligand to design and synthesize the first selective and potent of ROR1 PROTACs[1].
Product Specifications
UNSPSC
12352005
Target
ROR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CCN1CCC(NC2=C3C(NC(C4=CC=C(N5CCNCC5)C=C4)=N3)=NC=C2Br)CC1
Molecular Formula
C23H30BrN7
Molecular Weight
484.44
References & Citations
[1]Li J, et al. Discovery of the first potent ROR1 degrader for the treatment of non-small cell lung cancer. Eur J Med Chem. 2025 Mar 15;286:117325.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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