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ROR1 ligand-1

ROR1 ligand-1 (9-1) is a ligand for PROTACT ROR1 degrader-1. ROR1 ligand-1 connects with VHL-type or CRBN ligand to design and synthesize the first selective and potent of ROR1 PROTACs[1].

Product Specifications

UNSPSC

12352005

Target

ROR

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

CCN1CCC(NC2=C3C(NC(C4=CC=C(N5CCNCC5)C=C4)=N3)=NC=C2Br)CC1

Molecular Formula

C23H30BrN7

Molecular Weight

484.44

References & Citations

[1]Li J, et al. Discovery of the first potent ROR1 degrader for the treatment of non-small cell lung cancer. Eur J Med Chem. 2025 Mar 15;286:117325.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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