FKBP12 ligand-1
FKBP12 ligand-1 is a targeting protein ligand of MC-25B , which is a specific FKBP12 PROTAC[1].
Product Specifications
CAS Number
178446-02-1
UNSPSC
12352005
Target
FKBP; Ligands for Target Protein for PROTAC
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC(C=C1CC[C@H](C2=CC(OCC(O)=O)=CC=C2)OC([C@H]3N(CCCC3)C(C(C(C)(C)CC)=O)=O)=O)=C(C=C1)OC
Molecular Formula
C32H41NO9
Molecular Weight
583.67
References & Citations
[1]Campos MA, et al. Discovery of DCAF16 Binders for Targeted Protein Degradation. ACS Chem Biol. 2025 Feb 21;20 (2) :479-488.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FKBP12
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