FKBP12 ligand-1

FKBP12 ligand-1 is a targeting protein ligand of MC-25B (HY-170983), which is a specific FKBP12 PROTAC[1].

Product Specifications

CAS Number

[178446-02-1]

UNSPSC

12352005

Target

FKBP; Ligands for Target Protein for PROTAC

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

COC(C=C1CC[C@H](C2=CC(OCC(O)=O)=CC=C2)OC([C@H]3N(CCCC3)C(C(C(C)(C)CC)=O)=O)=O)=C(C=C1)OC

Molecular Formula

C32H41NO9

Molecular Weight

583.67

References & Citations

[1]Campos MA, et al. Discovery of DCAF16 Binders for Targeted Protein Degradation. ACS Chem Biol. 2025 Feb 21;20 (2) :479-488.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

FKBP12

Curated Selection

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