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FKBP12 Ligand-Linker Conjugate 1

FKBP12 Ligand-Linker Conjugate 1 is the conjugate composed of a target protein ligand for FKBP12 and a linker. FKBP12 Ligand-Linker Conjugate 1 can be used for synthesis of PROTAC degrader MC-25B.

Product Specifications

CAS Number

2765059-01-4

UNSPSC

12352005

Target

FKBP; Target Protein Ligand-Linker Conjugates

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

NCCCOCCOCCOCCCNC(COC1=CC=CC([C@H](OC([C@@H]2CCCCN2C(C(C(C)(C)CC)=O)=O)=O)CCC3=CC(OC)=C(OC)C=C3)=C1)=O

Molecular Formula

C42H63N3O11

Molecular Weight

785.96

References & Citations

[1]Campos MA, et al., Discovery of DCAF16 Binders for Targeted Protein Degradation. ACS Chem Biol. 2025 Feb 21;20 (2) :479-488.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

FKBP12

Frequently Asked Questions

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