FKBP12 Ligand-Linker Conjugate 1
FKBP12 Ligand-Linker Conjugate 1 is the conjugate composed of a target protein ligand for FKBP12 and a linker. FKBP12 Ligand-Linker Conjugate 1 can be used for synthesis of PROTAC degrader MC-25B (HY-170983) [1].
Product Specifications
CAS Number
[2765059-01-4]
UNSPSC
12352005
Target
FKBP; Target Protein Ligand-Linker Conjugates
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NCCCOCCOCCOCCCNC(COC1=CC=CC([C@H](OC([C@@H]2CCCCN2C(C(C(C)(C)CC)=O)=O)=O)CCC3=CC(OC)=C(OC)C=C3)=C1)=O
Molecular Formula
C42H63N3O11
Molecular Weight
785.96
References & Citations
[1]Campos MA, et al., Discovery of DCAF16 Binders for Targeted Protein Degradation. ACS Chem Biol. 2025 Feb 21;20 (2) :479-488.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FKBP12
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