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E3 ligase Ligand 57

E3 ligase Ligand 57 is an E3 ligase ligand of MC-25B (HY-170983) which is a specific FKBP12 PROTAC[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(O)CN1CCN(C2=CC=CC(C(N3CCC(N(C4CC4)C(CCl)=O)CC3)=O)=C2)CC1

Molecular Formula

C23H31ClN4O4

Molecular Weight

462.97

References & Citations

[1]Campos MA, et al. Discovery of DCAF16 Binders for Targeted Protein Degradation. ACS Chem Biol. 2025 Feb 21;20 (2) :479-488.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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