E3 Ligase Ligand-linker Conjugate 166
E3 Ligase Ligand-linker Conjugate 166 is the conjugate composed of a E3 ligase ligand and a linker. E3 Ligase Ligand-linker Conjugate 166 can be used for synthesis of PROTAC CDK9 degrader-11.
Product Specifications
CAS Number
2930001-60-6
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(CC1)NC(C1NC2=CC=CC(N(CC3)CCN3CC4CCN(C(OC(C)(C)C)=O)CC4)=C2)=O
Molecular Formula
C26H39N5O4
Molecular Weight
485.62
References & Citations
[1]Wang Y, et al., Identification of a Potent and Selective CDK9 Degrader as a Targeted Therapeutic Option for the Treatment of Small-Cell Lung Cancer. J Med Chem. 2025 Feb 13;68 (3) :2528-2550.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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