UG-650
UG-650 is a non-Gemini analog of UVB1 that combines the structural features of UVB1 and MC 1288. UG-650 can bind to the vitamin D receptor (VDR) and inhibit the proliferation of MCF-7 cells and the migration of MC3T3-E1 cells[1].
Product Specifications
UNSPSC
12352211
Target
VD/VDR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](CC(CCC(C)(O)C)=C)C)([H])[C@]3(C)CCC\2
Molecular Formula
C29H46O3
Molecular Weight
442.67
References & Citations
[1]Gómez-Bouzó U, et al. Design, synthesis and biological evaluation of a novel non-Gemini analog of UVB1 and crystal structure of its complex with the vitamin D receptor. Bioorg Chem. 2025 Feb 4;157:108239.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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