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UG-650

UG-650 is a non-Gemini analog of UVB1 that combines the structural features of UVB1 and MC 1288. UG-650 can bind to the vitamin D receptor (VDR) and inhibit the proliferation of MCF-7 cells and the migration of MC3T3-E1 cells[1].

Product Specifications

UNSPSC

12352211

Target

VD/VDR

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](CC(CCC(C)(O)C)=C)C)([H])[C@]3(C)CCC\2

Molecular Formula

C29H46O3

Molecular Weight

442.67

References & Citations

[1]Gómez-Bouzó U, et al. Design, synthesis and biological evaluation of a novel non-Gemini analog of UVB1 and crystal structure of its complex with the vitamin D receptor. Bioorg Chem. 2025 Feb 4;157:108239.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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