LASSBio-1985
LASSBio-1985 is an NHLd inhibitor (nucleoside hydrolase from Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. LASSBio-1985 exhibits selective toxicity against Leishmania parasites, with no toxicity to mammalian cells, making it a promising candidate for research in the field of anti-infective therapies[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(O)C1=CC=C(/C=N/NC([C@]2(O)C[C@@H](O)[C@H](OC(C)(C)O3)[C@H]3C2)=O)C=C1
Molecular Formula
C18H22N2O7
Molecular Weight
378.38
References & Citations
[1]Alves MA, et al. The discovery of a new uncompetitive inhibitor of nucleoside hydrolase from Leishmania donovani. Bioorg Chem. 2025 Mar;156:108209.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-170963/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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