SDUY817
SDUY817 is a dual APN/NEP inhibitor, with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. SDUY817 exerts analgesic effects in a concentration- and time-dependent manner, and can be used for research in the field of neuropathic pain disorders[1].
Product Specifications
UNSPSC
12352005
Target
Aminopeptidase; Neprilysin
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Smiles
O=C(N[C@H](CC1=CNC2=C1C=CC=C2)C(NO)=O)C3=CC=CC(I)=C3
Molecular Formula
C18H16IN3O3
Molecular Weight
449.24
References & Citations
[1]Zhang N, et al. Synthesis and biological evaluation of new dual APN/NEP inhibitors as potent analgesics. Bioorg Chem. 2025 Mar;156:108210.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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