TACC3 inhibitor 2
TACC3 inhibitor 2 (Compound 13b) is a TACC3 inhibitor with an IC50 of 200 nM. TACC3 inhibitor 2 can induce mitotic arrest, cell apoptosis (Apoptosis), and DNA damage. TACC3 inhibitor 2 can be used for cancer research[1].
Product Specifications
CAS Number
[2642351-96-8]
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
CC1CCN(C2=NC=CC(NC3=CC(C4=CC=C(OC)C=C4F)=NO3)=N2)CC1
Molecular Formula
C20H22FN5O2
Molecular Weight
383.42
References & Citations
[1]Lengerli D, et al. Isoxazole-pyrimidine derivatives as TACC3 inhibitors: A novel modality to targeted cancer therapy. Bioorg Chem. 2025 Mar;156:108204.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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