BTN3A1 ligand-1
BTN3A1 ligand-1 (Compound 26b) is a triazole-containing aryl/acyloxyalkyl phosphonate prodrug. BTN3A1 ligand-1 can stimulate T cell proliferation (EC50: 0.49 nM) and interferon γ secretion. BTN3A1 ligand-1 has certain plasma stability and can be used in related immunotherapy research[1].
Product Specifications
UNSPSC
12352005
Target
Drug Intermediate
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CN(C2=CC=C(F)C=C2)N=N1)OCOP(OC3=CC=CC=C3)(CC/C=C(C)/COC(C)=O)=O
Molecular Formula
C24H25FN3O7P
Molecular Weight
517.44
References & Citations
[1]Singh U, et al. Synthesis and evaluation of triazole-containing aryl/acyloxy prodrugs of a BTN3A1 ligand. Eur J Med Chem. 2025 Apr 5;287:117345.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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